Synuclein Antibodies
Synucleins are presynaptic proteins involved in synaptic vesicle regulation, and pathological α‑synuclein aggregation defines synucleinopathies such as Parkinson’s disease and dementia with Lewy bodies1,2. β‑synuclein has emerged as a sensitive marker of early synaptic degeneration, with elevated plasma levels indicating early Alzheimer’s‑related synaptic injury3. β‑synuclein increases are detectable even in asymptomatic autosomal‑dominant Alzheimer’s disease, supporting its value for early disease staging4.
Our various monoclonal antibodies targeting α‑ and β‑synuclein further enable the development of immunoassays for synuclein‑related pathology research.
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