Insights
Influence of automation on Aβ1-42/Aβ1-40 ratio and its use
Automation is an important step in the direction of more standardization as it limits the number of manual handling steps and therefore minimizes...
Mar 16, 2020
Comparison of Aβ1-42/Aβ1-40 ratio with other ratios
CSF Aβ1-42/Aβ1-40 is a tool to normalize values of patients with different amyloid levels, as other ratios might be seen more as interpretation tools...
Mar 2, 2020
INNO-LiPA® HPV Genotyping Extra II for use on self-collected first-void urine samples
HPV (Human Papilloma Virus) is a sexually transmitted virus. Certain genotypes of this virus are known to cause cancers in both men and women, but...
Feb 11, 2020
How to work with Aβ1-42/Aβ1-40 ratio
One cause of discordant results can be the preanalytical conditions, e.g. when laboratories use tubes that bind certain proteins. Aβ1-42 adsorption is...
Feb 5, 2020
Improvement of AD risk scores by use of the Aβ1-42/Aβ1-40 ratio
Different scores have been developed to provide an interpretation of biomarker results for AD diagnosis or risk prediction. Here we will give two...
Jan 20, 2020
Aβ1-42/Aβ1-40 ratio for interpretation of discordant results
By use of the Aβ1-42/Aβ1-40 ratio, discordant results (i.e. when amyloid and tau biomarkers are not concordant) can be improved. However, while the...
Jan 9, 2020
From Classification to disease activity
While IPF is the classic fibrosing ILD, clinical data suggest that there is a larger group of patients with differing clinical ILD diagnoses who...
Dec 17, 2019
Recent research has shown that serum and bronchoalveolar lavage fluid level of KL-6 has an important value in the diagnosis, treatment assessment and...
Dec 2, 2019
Early, easy, efficient and cost-effective diagnosis of Cystic Fibrosis
Cystic Fibrosis is one of the most frequent life threatening inherited diseases. If detected early, effective treatment can be started improving...
Nov 28, 2019
Use of the Aβ1-42/Aβ1-40 ratio to improve accuracy of AD diagnosis
It is widely agreed that, since cerebrospinal fluid (CSF) is in direct contact with the central nervous system (CNS), analytes measured in this body...
Nov 22, 2019
Use of serum biomarkers in progressive fibrosing ILDs
Based on the results from a number of reports investigating KL-6/MUC1, the serum levels of KL-6/MUC1 are useful for 1) detecting the presence of...
Nov 18, 2019