Insights
How to work with Aβ1-42/Aβ1-40 ratio
One cause of discordant results can be the preanalytical conditions, e.g. when laboratories use tubes that bind certain proteins. Aβ1-42 adsorption is...
Feb 5, 2020
Improvement of AD risk scores by use of the Aβ1-42/Aβ1-40 ratio
Different scores have been developed to provide an interpretation of biomarker results for AD diagnosis or risk prediction. Here we will give two...
Jan 20, 2020
Aβ1-42/Aβ1-40 ratio for interpretation of discordant results
Jan 9, 2020
From Classification to disease activity
While IPF is the classic fibrosing ILD, clinical data suggest that there is a larger group of patients with differing clinical ILD diagnoses who...
Dec 17, 2019
Recent research has shown that serum and bronchoalveolar lavage fluid level of KL-6 has an important value in the diagnosis, treatment assessment and...
Dec 2, 2019
Early, easy, efficient and cost-effective diagnosis of Cystic Fibrosis
Cystic Fibrosis is one of the most frequent life threatening inherited diseases. If detected early, effective treatment can be started improving...
Nov 28, 2019
Use of the Aβ1-42/Aβ1-40 ratio to improve accuracy of AD diagnosis
It is widely agreed that, since cerebrospinal fluid (CSF) is in direct contact with the central nervous system (CNS), analytes measured in this body...
Nov 22, 2019
Use of serum biomarkers in progressive fibrosing ILDs
Based on the results from a number of reports investigating KL-6/MUC1, the serum levels of KL-6/MUC1 are useful for 1) detecting the presence of...
Nov 18, 2019
ILD diagnosis – current professional practice
Accurate diagnosis of IPF is critical, as other forms of ILD that have similar clinical presentations to IPF require different treatment strategies.
Nov 5, 2019
KL-6 in Lung Diseases: Current classification of interstitial lung diseases
Interstitial lung diseases (ILDs) represent a large, heterogeneous group of more than 200 different entities, most of which are classified as rare...
Oct 24, 2019
Alzheimer’s disease, which is the most common form of dementia, is an incurable degenerative disease. Neurons in certain parts of the brain are...
Sep 30, 2019