CAP Today Article - Alzheimer's blood tests poised to lead

Mar 31, 2026

For a pathology that is invariably associated with dimming—of memory, of relationships, of personality—

Alzheimer’s disease has been linked to remarkably bright news as of late. Blood-based biomarkers, including two that garnered FDA approval last year, have cracked open the door to earlier diagnoses and therapeutic interventions, as well as the potential to reach more patients.

In May 2025, the Lumipulse G pTau 217α-Amyloid 1-42 plasma ratio test (Fujirebio Diagnostics) was approved to aid in diagnosing Alzheimer’s disease, specifically for early detection of Alzheimer’s-associated amyloid plaques in patients 55 and older who exhibit signs/symptoms of the disease. And last October, the FDA cleared the Elecsys pTau181 plasma test (Roche Diagnostics) for use in primary care settings, to rule out Alzheimer’s disease in patients 55 and older who are exhibiting signs/symptoms of cognitive decline.

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