INNO-LIA^® HTLV I/II Score

The antigens are either recombinant proteins or synthetic peptides that are purified and fixed on a nylon membrane.

The antigenicity exhibited by these proteins and peptides is either common to HTLV I and HTLV II antibodies or type-specific to one of the two viruses allowing confirmation and discrimination in a single assay.

Two gag bands (p19 I/II, p24 I/II) and two env (gp46 I/II, gp21 I/II) bands are applied as non-type-specific antigens, used to confirm the presence of antibodies against HTLV I/II.

The type-specific antigens (gag p19-I, env gp46-I) specific for HTLV I and (env gp46-II) specific for HTLV II, enable differentiation of HTLV I and HTLV II infections.
 

Features & Benefits

• Complete answer in one test: confirmation and discrimination

• Low follow-up rate

• Low indeterminate rate

• Optimal specificity in screened-negative blood donors: 99.7% (304/305)

• Optimal sensitivity for HTLV I (100%; 218/218) and HTLV II (100%; 112/112)

• Color-coded reagents

• Ready-to-use reagents

• Four control lines to monitor 1) non-specific reactivity, 2) sample addition,  3) and 4) color development steps

• Fully automated strip processing possible using TENDIGO™, Auto-LIA™ 48, AutoBlot 3000(H) or Roboblot^®

• Objective, automated reading and interpretation of the strips possible using LiRAS® for Infectious Diseases