INNO-LIA® HIV I/II Score

The clearest answer in HIV confirmation

Line immunoassay for the confirmation and discrimination of antibodies to HIV-1, HIV-1 group O and HIV-2 in human serum and plasma.

    CE marked
    INNO-LIA® HIV I/II Score

    Product number 80540

    20 Tests
    Please contact your local Fujirebio representative for the availability of this product in your country.

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    • Details

       

       

       
      Features & Benefits

      • All major HIV strains detectable with one strip: HIV-1, HIV-2, and HIV-1 group O
      • Optimal specificity in screened-negative blood donors: 96.7% (290/300)
      • High sensitivity in BBI panels
      • Short and overnight procedures
      • Color-coded reagents
      • Ready-to-use reagents
      • Four control lines to monitor 1) non-specific reactivity, 2) sample addition,  3) and 4) color development steps
      • Fully automated strip processing possible using TENDIGO™, Auto-LIA™ 48, Auto-LiPA™ 48, AutoBlot 3000(H) or Roboblot®
      • Objective, automated reading and interpretation of the strips possible using LiRAS® for Infectious Diseases

       
      Background

      Antibodies to human immunodeficiency virus (HIV) have been detected in most patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC), and in many asymptomatic individuals belonging to high-risk groups. Enzyme-linked immunosorbent assays (ELISA) are widely used to screen human blood and plasma samples for the presence of these HIV antibodies.

      However, since false-positive reactions have frequently been observed with current ELISA tests, it is strongly recommended to confirm repeatedly reactive samples by use of other reliable techniques (such as the INNO-LIA HIV I/II Score). Recombinant proteins and synthetic peptides from HIV-1 and HIV-2, and a synthetic peptide from HIV-1 group O, are coated as discrete lines on a nylon strip with plastic backing.

      The INNO-LIA HIV I/II Score assay contains sequences derived from HIV-O sequences to allow the optimal detection of infections caused by this group of viruses. To allow the broad spectrum detection of all HIV infections, the INNO-LIA HIV I/II Score assay also contains separate lines for the differentiation of HIV-1 and HIV-2 infections.

      This is important, as HIV-2 is less virulent, resulting in a better prognosis for the patient.

       

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