INNO-LIA® HIV I/II Score

The clearest answer in HIV confirmation

Line immunoassay for the confirmation and discrimination of antibodies to HIV-1, HIV-1 group O and HIV-2 in human serum and plasma.

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    CE marked (IVDR)
    INNO-LIA® HIV I/II Score

    Product number 80540

    20 Tests
    Please contact your local Fujirebio representative for the availability of this product in your country.

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    • Details

       

       

       
      Features & Benefits

      • All major HIV strains detectable with one strip: HIV-1, HIV-2, and HIV-1 group O
      • Optimal specificity in screened-negative blood donors: 96.7% (290/300)
      • High sensitivity in BBI panels
      • Short and overnight procedures
      • Color-coded reagents
      • Ready-to-use reagents
      • Four control lines to monitor 1) non-specific reactivity, 2) sample addition,  3) and 4) color development steps
      • Fully automated strip processing possible using TENDIGO™, Auto-LIA™ 48, Auto-LiPA™ 48, AutoBlot 3000(H) or Roboblot®
      • Objective, automated reading and interpretation of the strips possible using LiRAS® for Infectious Diseases

       
      Background

      Antibodies to human immunodeficiency virus (HIV) have been detected in most patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC), and in many asymptomatic individuals belonging to high-risk groups. Enzyme-linked immunosorbent assays (ELISA) are widely used to screen human blood and plasma samples for the presence of these HIV antibodies.

      However, since false-positive reactions have frequently been observed with current ELISA tests, it is strongly recommended to confirm repeatedly reactive samples by use of other reliable techniques (such as the INNO-LIA HIV I/II Score). Recombinant proteins and synthetic peptides from HIV-1 and HIV-2, and a synthetic peptide from HIV-1 group O, are coated as discrete lines on a nylon strip with plastic backing.

      The INNO-LIA HIV I/II Score assay contains sequences derived from HIV-O sequences to allow the optimal detection of infections caused by this group of viruses. To allow the broad spectrum detection of all HIV infections, the INNO-LIA HIV I/II Score assay also contains separate lines for the differentiation of HIV-1 and HIV-2 infections.

      This is important, as HIV-2 is less virulent, resulting in a better prognosis for the patient.

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      To read the end user conditions of sale for this product please visit our Resource center.

    • Citations

      The BIOZ badges associated with Fujirebio products include peer-reviewed citations derived from scientific studies using Fujirebio products. Please note that the peer-reviewed citations do not reflect the regulatory status of Fujirebio products. Users should refer to the specific product documentation and any (clinical) claims made therein in order to ensure compliant use. For each country or geographic region, users must verify the related regulatory status of the Fujirebio product.

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