Lumipulse® G TPOAb (Anti-Thyroid Peroxidase Antibodies)
Immunoreaction cartridges forin vitro diagnostic (IVD) use with the LUMIPULSE G System for the quantitative measurement of Anti-Thyroid Peroxidase Antibodies (TPOAb) in serum or plasma. Includes calibrators.
The assay utilises proven CLEIA (ChemiLuminescent Enzyme Immunoassay) technology with results that are available in up to 35 minutes.
Product number 230572
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Details
CLEIA - ChemiLuminescent Enzyme Immunoassay
Test principle: Two-Step sandwich assay
Clinical backgroundTPOAb
Thyroid autoantibodies appear mostly with the presence of lymphocytes in the targeted organ and Thyroid Peroxidase Antibodies is one of these autoantibodies.
These autoantibodies affect different targets in the thyroid gland, and although a healthy patient may be positive for this autoantibody, this does not mean that they will necessarily present with thyroid problems although they may have thyroid dysfunction over time.
The major antigen has been recently identified as thyroid peroxidase (TPO), which plays an important role in thyroid hormone synthesis.
Consequently, assay of the anti-thyroid peroxidase antibody (TPOAb) titer, instead of the anti-microsome antibody titer, has come to be used as a diagnostic marker of autoimmune thyroid disease.
See the LUMIPULSE G1200 working in this video:
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