CanAg® CA125 EIA

CA125 is a high molecular weight mucin-type glycoprotein, originally defined by the Oc125 monoclonal antibody (MAb) established by Bast et al.1. Different epitopes, co-expressed with the Oc125 epitope on the CA125 antigen, have been used for the development of heterologous assays for determination of the CA125 antigen2. The CA125 EIA is based on two mouse monoclonal antibodies, Ov197 and Ov185, directed against two independent epitopes of the protein core of the CA125 antigen3, 4. Assays for CA125 are frequently used to monitor patients with gynecological malignancies such as epithelial ovarian cancer5.


  1. Bast R., Feeney M., Lazarus H., Nadler L., Colvin R., Knapp R., (1981). Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 68: 1331 - 1337.

  2. O'Brien T, Raymond L, Bannon G, Ford D, Hardardottir H, Miller F, Quirk J (1991). New monoclonal antibodies identify the glycoprotein carrying the CA125 epitope. Am J Obstet Gynecol 165: 1857 - 1864.

  3. Nilsson O, Jansson E-L, Dahlen U, Nilsson K, Nustad K, Högberg T, Lindholm L (1994). In: Current Tumor Diagnosis: Applications, Clinical Relevance, Research, Trends. Ed R. Klapdor. Zuckswerdt Verlag München, pp 401-405.

  4. Nustad K. et al., (1996) Specificity and affinity of 26 monoclonal antibodies against the CA125 antigen: First report from the ISOBM TD-1 Workshop. Tumor Biol 17:196-219.

  5. Bonfrer J., Duffy M., Radtke, M., Segurado O., Torre G., van Dalen A., Zwirner M. (1999) Tumor markers in gynecological cancers-EGTM recommendations. Anticancer Research 19:2785-2820.

Contact sales for information
CE marked
CanAg CA125 EIA

Product number 400-10

For 96 determinations
Please contact your local Fujirebio representative for the availability of this product in your country.
  • Product inquiry

    The provision of your data implies your consent to the processing of your data in our database and, depending on the option you choose, to receiving our monthly newsletter by e-mail.

    For more information on how we process your personal data and regarding the rights you have in this respect, we refer to our privacy policy, which we hold at your disposal HERE.

    If you no longer wish to receive our newsletter, you have the option to unsubscribe via the ‘unsubscribe’ tool at the bottom of the newsletter. If you want to have your data removed from our database, please contact us at: